NORD: National Organization for Rare Disorders.Department of Health and Human Services Protein C deficiency. National Library of Medicine: MedlinePlus. Department of Health and Human Services Blood Tests. National Heart, Lung, and Blood Institute.Vienna (VA): National Blood Clot Alliance Protein S and Protein C Deficiency Resources. Test ID: PSTF Protein S Antigen, Plasma Clinical and Interpretive. Mayo Foundation for Medical Education and Research c1995–2022. Mayo Clinic: Mayo Medical Laboratories.Treasure Island (FL): StatPearls Publishing 2022 Jan. Cleveland Clinic: Health Library: Protein S Deficiency.Learn more about laboratory tests, reference ranges, and understanding results. If you have questions about your results or how to manage a protein C or S deficiency, talk with your provider. Avoiding other things that can increase your risk of blood clots, including:.Treating the condition that caused an acquired deficiency.Taking medicines (blood thinners, also called "anticoagulants") to help prevent too much clotting.You may be able to lower your risk of blood clots by: Your provider may recommend treatment depending on your test results and health history. With both inherited and acquired deficiencies, treatment may help reduce your risk of developing blood clots. In certain cases, acquired deficiencies may get worse over time. If your protein C or S deficiency is acquired, the deficiency may be temporary or long-lasting. But it does mean that your risk for developing a clot will be increased for the rest of your life. Having an inherited deficiency doesn't mean that you'll develop a blood clot. If your provider thinks your protein C or S deficiency is inherited, you may need a genetic test to find out for sure. Your level of risk depends on how abnormal your test results are. Lower than normal levels of protein C or S, or proteins that aren't working well, mean that you have a higher risk of developing a blood clot. Higher than normal levels of protein C or S are not known to cause any health problems. Other names: protein C antigen, protein S antigen, PC, PS, free PS, autoprothrombin IIA But they are often done at the same time. There are separate tests for protein C and S. That means that your condition is caused by a change in a gene that one or both of your parents passed down to you. In rare cases, protein C or protein S deficiencies are inherited.
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